Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 7/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135725 | 0.92 | LTA4H (0.39) | CSNK2A2CSNK2BMAPTCDC7CDK2 | |
| SCHEMBL9305127 | 0.91 | MERTK (0.41) | CSNK2A2CSNK2BMAPTCDC7CDK2 | |
| SCHEMBL9258008 | 0.88 | NAMPT (0.39) | MAPTCDC7CDK2NAMPT | |
| SCHEMBL9303594 | 0.87 | HRH1 (0.36) | CSNK2A2CSNK2BNAMPTCYP2D6ALDH1A1 | |
| SCHEMBL8137072 | 0.86 | ALDH1A1 (0.39) | MAPTNAMPTCYP2C9ALDH1A1CYP1A2 | |
| SCHEMBL9306122 | 0.86 | HSD17B10 (0.47) | LMNAALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL8134231 | 0.84 | HSD17B10 (0.46) | LMNAALDH1A1HTT | |
| SCHEMBL8134112 | 0.83 | CRHR1 (0.36) | — | |
| SCHEMBL9304657 | 0.83 | KIF11 (0.41) | NAMPTNPSR1KCNH2SRCBRAF | |
| SCHEMBL8138744 | 0.83 | CYP2D6 (0.42) | MAPTCDC7CDK2NAMPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296491-A | Pyrazolo[4,3-c]pyridines and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | claimed |