Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2112745 | 0.73 | IKBKB (0.56) | IKBKBALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9302720 | 0.71 | KIF11 (0.40) | IKBKBALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL26054630 | 0.68 | MKNK1 (0.65) | ALDH1A1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL8614787 | 0.67 | FBP1 (0.33) | ALDH1A1HSD17B10MEN1KMT2AHPGD | |
| SCHEMBL20022402 | 0.67 | IKBKB (0.58) | IKBKBALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL10937913 | 0.67 | PIN1 (0.51) | ALDH1A1HSD17B10KMT2AKDM4EHPGD | |
| SCHEMBL17773156 | 0.66 | KMO (0.67) | ALDH1A1MEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9424430 | 0.66 | FBP1 (0.47) | IKBKBALDH1A1HPGD | |
| SCHEMBL9302312 | 0.65 | KIF11 (0.49) | ALDH1A1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL16997515 | 0.65 | NPC1 (0.59) | ALDH1A1HSD17B10KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340815-A | Inhibitors of 5-lipoxygenase and/or cyclooxygenase | WARNER-LAMBERT COMPANY (US) | 1994-08-23 | — | — | US | disclosed |
| US-5302597-A | Enzyme inhibitors | WARNER-LAMBERT COMPANY (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0569491-A4 | 2-SUBSTITUTED-4,6-DI-TERTIARY-BUTYL-5-HYDROXY-1,3-PYRIMIDINES USEFUL AS ANTIINFLAMMATORY AGENTS | — | 1993-11-24 | — | — | EP | disclosed |
| EP-0569491-A1 | 2-SUBSTITUTED-4,6-DI-TERTIARY-BUTYL-5-HYDROXY-1,3-PYRIMIDINES USEFUL AS ANTIINFLAMMATORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-11-18 | — | — | EP | disclosed |
| US-5248682-A | Inhibitors of lipoxygenase and cyclooxygenase | WARNER-LAMBERT COMPANY (US) | 1993-09-28 | — | — | US | disclosed |
| US-5177079-A | Antiallergen, antiulcer | WARNER-LAMBERT COMPANY (US) | 1993-01-05 | — | — | US | disclosed |
| WO-1992013536-A1 | 2-SUBSTITUTED-4,6-DI-TERTIARY-BUTYL-5-HYDROXY-1,3-PYRIMIDINES USEFUL AS ANTIINFLAMMATORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-08-20 | — | — | WO | disclosed |