Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | UBE2M | P61081 | 2/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301121 | 0.87 | ACHE (0.45) | SIGMAR1LTA4HDRD4MAPTMAPK1 | |
| SCHEMBL9302817 | 0.86 | AIMP2 (0.53) | SIGMAR1LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL9301593 | 0.84 | SIGMAR1 (0.48) | SIGMAR1LTA4HKDM4EALDH1A1DRD4 | |
| SCHEMBL9303117 | 0.81 | LTA4H (0.48) | LTA4HMAPTMAPK1 | |
| SCHEMBL9300946 | 0.80 | NPC1 (0.52) | SIGMAR1LTA4HKDM4EALDH1A1 | |
| SCHEMBL9301620 | 0.80 | RBP4 (0.48) | ALDH1A1UBE2MDCUN1D1LMNA | |
| SCHEMBL9302321 | 0.79 | ATM (0.42) | SIGMAR1LTA4HKDM4EALDH1A1MAPT | |
| SCHEMBL9301653 | 0.77 | ACHE (0.47) | SIGMAR1LTA4HALDH1A1LMNAMAPT | |
| SCHEMBL9302789 | 0.76 | ADRA1D (0.56) | SIGMAR1ALDH1A1LMNAMAPTKCNH2 | |
| SCHEMBL9301861 | 0.73 | BACE1 (0.49) | ALDH1A1DRD4DCUN1D1LMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |