Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847735 | 0.87 | HTT (0.43) | HTTMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9301681 | 0.85 | HTT (0.42) | HTTMAPTGPR119DPP4MAP4K4 | |
| SCHEMBL9303256 | 0.85 | GAA (0.45) | HTTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9847732 | 0.77 | HTT (0.43) | HTTMAPTALDH1A1GPR119DPP4 | |
| SCHEMBL9301682 | 0.76 | RORC (0.42) | HTTMAPTGPR119DPP4SMN1; SMN2 | |
| SCHEMBL9301581 | 0.76 | HTT (0.50) | HTTMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9847719 | 0.76 | DRD3 (0.47) | HTTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL21937028 | 0.73 | MAPT (0.51) | HTTMAPTALDH1A1GPR119DPP4 | |
| SCHEMBL9302442 | 0.73 | RORC (0.41) | HTTMAPTGPR119DPP4SMN1; SMN2 | |
| SCHEMBL9303809 | 0.73 | HTT (0.41) | HTTMAPTALDH1A1GPR119SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |