Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303507 | 0.82 | KDM4E (0.47) | RAB9ANPC1KDM4ESMN1; SMN2POLB | |
| SCHEMBL9302237 | 0.81 | F10 (0.49) | RAB9ANPC1KDM4ESMN1; SMN2POLB | |
| SCHEMBL9303104 | 0.81 | NPC1 (0.49) | RAB9ANPC1KDM4ESMN1; SMN2POLB | |
| SCHEMBL9303327 | 0.81 | RAB9A (0.44) | RAB9ANPC1KDM4ESMN1; SMN2POLB | |
| SCHEMBL9302652 | 0.81 | PLAU (0.48) | RAB9ANPC1POLBKMT2AF10 | |
| SCHEMBL9303230 | 0.81 | NPC1 (0.52) | RAB9ANPC1KDM4ESMN1; SMN2POLB | |
| SCHEMBL9303445 | 0.80 | NPC1 (0.54) | RAB9ANPC1KDM4ESMN1; SMN2POLB | |
| SCHEMBL9303274 | 0.80 | PLAU (0.62) | RAB9ANPC1KDM4ESMN1; SMN2POLB | |
| SCHEMBL9302810 | 0.78 | NPC1 (0.49) | RAB9ANPC1KDM4ESMN1; SMN2POLB | |
| SCHEMBL9303221 | 0.78 | NPC1 (0.46) | RAB9ANPC1KDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |