Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | P62805 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303523 | 0.90 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9303274 | 0.84 | PLAU (0.62) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9302624 | 0.84 | PLAU (0.53) | NPC1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9303439 | 0.83 | NPC1 (0.45) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9304163 | 0.81 | PTGES (0.54) | NPC1RAB9AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9302832 | 0.81 | RXFP1 (0.50) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9302926 | 0.81 | RAB9A (0.50) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9302237 | 0.80 | F10 (0.49) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9303221 | 0.80 | NPC1 (0.46) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9303445 | 0.79 | NPC1 (0.54) | NPC1RAB9AKDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |