Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869620 | 0.92 | SIGMAR1 (0.49) | SIGMAR1TMEM97FDPS | |
| SCHEMBL9304044 | 0.90 | SIGMAR1 (0.42) | SIGMAR1TMEM97KMT2A | |
| SCHEMBL9303707 | 0.84 | SCN1A (0.38) | SIGMAR1 | |
| SCHEMBL9304467 | 0.81 | UTS2R (0.35) | SIGMAR1TMEM97UTS2RAOC3 | |
| SCHEMBL9304202 | 0.81 | SIGMAR1 (0.46) | SIGMAR1TMEM97 | |
| Hydrochloric Acid SCHEMBL11610377 | 0.73 | SCN1A (0.57) | SIGMAR1TMEM97KMT2AFDPSAOC3 | |
| Hydrochloric Acid SCHEMBL11606157 | 0.73 | SIGMAR1 (0.45) | SIGMAR1TMEM97FDPSAOC3 | |
| SCHEMBL9304790 | 0.72 | TAAR1 (0.36) | SIGMAR1FDPSAOC3 | |
| SCHEMBL9303673 | 0.71 | CNR2 (0.34) | SIGMAR1TMEM97 | |
| SCHEMBL9303403 | 0.68 | SLC6A2 (0.43) | SIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505379-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-07-20 | — | — | EP | disclosed |
| US-5300516-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-05 | — | — | US | disclosed |