Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303673 | 0.93 | CNR2 (0.34) | TAAR1OPRM1OPRL1SIGMAR1TACR1 | |
| SCHEMBL9304060 | 0.92 | KDM4E (0.36) | OPRM1OPRL1FDPSTACR1SLC6A4 | |
| SCHEMBL9304467 | 0.92 | UTS2R (0.35) | AOC3SIGMAR1 | |
| SCHEMBL9302750 | 0.88 | DDB1 (0.37) | OPRM1OPRL1SLC6A3TACR1SLC6A4 | |
| SCHEMBL9869620 | 0.79 | SIGMAR1 (0.49) | TAAR1FDPSSLC6A3SIGMAR1SLC6A4 | |
| SCHEMBL9303006 | 0.73 | LMNA (0.37) | TAAR1OPRM1OPRL1HTR2AHTR2B | |
| SCHEMBL9304044 | 0.73 | SIGMAR1 (0.42) | SLC6A3SIGMAR1SLC6A4 | |
| SCHEMBL9304202 | 0.73 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL9303707 | 0.68 | SCN1A (0.38) | SIGMAR1SLC6A4 | |
| SCHEMBL9467170 | 0.67 | TSHR (0.47) | TAAR1OPRM1OPRL1SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505379-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-07-20 | — | — | EP | disclosed |
| US-5300516-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-05 | — | — | US | disclosed |
| WO-1991009014-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-06-27 | — | — | WO | disclosed |