Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869620 | 0.86 | SIGMAR1 (0.49) | SIGMAR1SLC6A4 | |
| SCHEMBL9304044 | 0.84 | SIGMAR1 (0.42) | SIGMAR1SLC6A4CYP3A4 | |
| SCHEMBL9303335 | 0.84 | SIGMAR1 (0.45) | SIGMAR1 | |
| SCHEMBL9304202 | 0.78 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL9303403 | 0.69 | SLC6A2 (0.43) | SIGMAR1SLC6A4CYP3A4 | |
| SCHEMBL9426568 | 0.68 | CHRM2 (0.39) | SIGMAR1SMPD1SLC6A4MAPK1 | |
| SCHEMBL9304790 | 0.68 | TAAR1 (0.36) | SIGMAR1SLC6A4 | |
| SCHEMBL9303673 | 0.67 | CNR2 (0.34) | SIGMAR1 | |
| SCHEMBL9304467 | 0.66 | UTS2R (0.35) | SIGMAR1 | |
| SCHEMBL20382495 | 0.66 | MAPK1 (0.50) | SIGMAR1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300516-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-05 | — | — | US | disclosed |
| WO-1991009014-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-06-27 | — | — | WO | disclosed |