Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38651331 | 0.76 | RAB9A (0.57) | TP53GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL27501139 | 0.76 | KCNMA1 (0.53) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4759867 | 0.72 | NPC1 (0.47) | TP53GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL9304572 | 0.72 | RAB9A (0.51) | TP53GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL7847251 | 0.71 | TP53 (0.65) | TP53GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL20715688 | 0.71 | TNF (0.68) | TP53GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL29072079 | 0.71 | ALOX5 (0.47) | GAAALDH1A1MAPT | |
| SCHEMBL9304768 | 0.70 | CYP19A1 (0.58) | TP53GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL9410966 | 0.69 | ALDH1A1 (0.51) | GAAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL30322779 | 0.69 | CYP11B1 (0.67) | TP53GAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374701-A | Crosslinkable polymers of high strength free of structural defects | HAY ALLAN S (CA) | 1994-12-20 | — | — | US | disclosed |
| WO-1993009079-A1 | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALAN S (CA) | 1993-05-13 | — | — | WO | disclosed |