Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276579 | 0.78 | BCL2L1 (0.39) | BCL2L1BADALDH1A1ALOX15HSD17B10 | |
| SCHEMBL27664477 | 0.77 | BCL2L1 (0.38) | BCL2L1BADALDH1A1ALOX15HSD17B10 | |
| SCHEMBL1923737 | 0.77 | CYP1A2 (0.33) | ALDH1A1CA1CA2TSHR | |
| SCHEMBL4630155 | 0.76 | CA2 (0.38) | CA1CA2CA6CDK2 | |
| SCHEMBL10817023 | 0.75 | CYP2D6 (0.36) | ALDH1A1LMNACYP3A4TSHRHTR1A | |
| SCHEMBL15351296 | 0.75 | TRPA1 (0.34) | ALDH1A1TRPA1 | |
| SCHEMBL9038110 | 0.72 | CA12 (0.39) | ALDH1A1ALOX15HSD17B10CA1CA2 | |
| SCHEMBL4776503 | 0.72 | MAPT (0.38) | ALDH1A1TDP1EGFRLMNAMAPT | |
| SCHEMBL6694442 | 0.72 | HTR1A (0.34) | HTR1A | |
| SCHEMBL7020118 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233078-A1 | USE OF SIGMA RECEPTOR LIGANDS IN OSTEOARTHRITIS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096125-A1 | USE OF SIGMA RECEPTOR LIGANDS IN OSTEOARTHRITIS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2016-06-23 | — | — | WO | disclosed |
| US-5278273-A | Additional polymer | FUJI PHOTO FILM CO., LTD. (JP) | 1994-01-11 | — | — | US | disclosed |
| EP-0000247-B1 | WATER-ABSORBENT STARCH COPOLYMERISATES AND METHOD FOR THEIR PREPARATION. | A.E. STALEY MANUFACTURING COMPANY (US) | 1982-08-04 | — | — | EP | disclosed |