Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452976 | 0.86 | LTA4H (0.40) | ALDH1A1TDP1FAAHCYP1A2CYP2C19 | |
| SCHEMBL2610137 | 0.85 | L3MBTL1 (0.42) | ALDH1A1KMT2AHPGDHTT | |
| SCHEMBL2610138 | 0.82 | TRPA1 (0.42) | ALDH1A1MEN1KMT2AAKR1C3TSHR | |
| SCHEMBL3295316 | 0.82 | TRPA1 (0.42) | ALDH1A1MEN1KMT2AAKR1C3TSHR | |
| SCHEMBL25800568 | 0.81 | TDP1 (0.35) | ALDH1A1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1825494 | 0.80 | ALPL (0.42) | ALDH1A1TDP1KMT2AMAOBSMN1; SMN2 | |
| SCHEMBL9863181 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TDP1PTGS1MEN1KMT2A | |
| SCHEMBL22714012 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHRLMNAGAA | |
| SCHEMBL1829082 | 0.79 | ALPL (0.36) | ALDH1A1TDP1LMNAGAAMAPT | |
| SCHEMBL7088040 | 0.78 | GAA (0.44) | ALDH1A1SMN1; SMN2TSHRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352836-A | Enantioselective lewis acid catalysts of the early transition metals | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| US-5231203-A | Enantioselective lewis acid catalysts of the early transition metals | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-07-27 | — | — | US | disclosed |
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4399296-A | TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |