Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 3/20 | 0.33 |
| ▸ | KDM4A | O75164 | 3/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.33 |
| ▸ | KDM3B | Q7LBC6 | 3/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 3/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140120 | 0.78 | GLA (0.34) | PLAT | |
| SCHEMBL7968120 | 0.76 | SPR (0.38) | NR4A3KDM6BKDM4AKDM4DHIF1AN | |
| SCHEMBL9138406 | 0.69 | L3MBTL1 (0.31) | L3MBTL1PLATGABRA1GABRA5GABRB2 | |
| SCHEMBL28921667 | 0.63 | KDM4E (0.44) | NR4A3HCAR2SPRKDM4EGABRP | |
| SCHEMBL7424613 | 0.63 | MMP2 (0.48) | KDM5BKDM5AKDM6BKDM4AKDM4D | |
| SCHEMBL3291164 | 0.62 | NR4A3 (0.44) | NR4A3L3MBTL1KDM4EGABRPGABRD | |
| SCHEMBL9140123 | 0.62 | KDM4C (0.33) | — | |
| SCHEMBL21893562 | 0.60 | KDM4E (0.45) | NR4A3HCAR2SPRKDM4EGABRP | |
| SCHEMBL7303922 | 0.60 | NR4A3 (0.42) | NR4A3KDM4EALDH1A1MAPTGAA | |
| SCHEMBL773204 | 0.60 | NR4A3 (0.78) | NR4A3ALDH1A1MAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354766-A | 2-Ethoxy-1-((2'(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl) biphenyl-4-yl)methyl)benzimidazole-7-carboxylic acid; hypotensive agents; CNS activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |