Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 9/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 9/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 9/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 9/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305797 | 0.84 | CASP3 (0.36) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL10759165 | 0.76 | PPARA (0.39) | CASP3SENP8SENP7SENP6 | |
| SCHEMBL18791159 | 0.74 | MMP1 (0.38) | NPC1GAAMAPK1RAB9AKMT2A | |
| SCHEMBL11121222 | 0.73 | TLR8 (0.31) | CASP3SENP8SENP7SENP6TLR8 | |
| SCHEMBL10759158 | 0.73 | PPARA (0.36) | CASP3SENP8SENP7SENP6 | |
| SCHEMBL14835983 | 0.72 | CASP3 (0.56) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL8359245 | 0.72 | CTRC (0.44) | NPC1GAAMAPK1RAB9ATLR8 | |
| SCHEMBL9305746 | 0.72 | CASP3 (0.38) | CASP3SENP8SENP7SENP6PCSK9 | |
| SCHEMBL9305543 | 0.72 | KMT2A (0.43) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL9305390 | 0.72 | GAA (0.43) | GAATLR8KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-B1 | HETEROCYCLICALLY SUBSTITUTED THIO(CYCLO)ALKANE POLYCARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |