Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.31 |
| ▸ | HPGD | P15428 | 6/20 | 0.31 |
| ▸ | GAA | P10253 | 5/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303910 | 0.82 | MEN1 (0.43) | KMT2AMEN1ALDH1A1CTRCTLR8 | |
| SCHEMBL9304728 | 0.72 | CASP3 (0.37) | KMT2AMEN1CTRCTLR8GAA | |
| SCHEMBL8359245 | 0.71 | CTRC (0.44) | KMT2AMEN1ALDH1A1CTRCTLR8 | |
| SCHEMBL9306655 | 0.71 | MEN1 (0.37) | KMT2AMEN1ALDH1A1PTGESEIF4A1 | |
| SCHEMBL9305390 | 0.71 | GAA (0.43) | KMT2AMEN1TLR8GAAHTT | |
| SCHEMBL9306662 | 0.70 | MEN1 (0.36) | KMT2AMEN1ALDH1A1EIF4A1KDM4E | |
| SCHEMBL9305399 | 0.68 | GAA (0.43) | KMT2AMEN1TLR8GAATSHR | |
| SCHEMBL9306399 | 0.68 | TLR8 (0.44) | KMT2AMEN1ALDH1A1TLR8ESR1 | |
| SCHEMBL16750381 | 0.67 | CTRC (0.38) | KMT2AMEN1ALDH1A1CTRCTLR8 | |
| SCHEMBL8989582 | 0.66 | CTRC (0.44) | KMT2AMEN1ALDH1A1CTRCTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |