Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 3/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 3/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720829 | 0.98 | ALDH1A1 (0.45) | ALDH1A1HSD17B10PSMD14COPS5PRMT5 | |
| Phenol SCHEMBL28809498 | 0.80 | HSD17B1 (0.33) | ALDH1A1HSD17B10CASP1KDM4ENPC1 | |
| Benzene SCHEMBL27557500 | 0.75 | LMNA (0.44) | ALDH1A1HSD17B10NPC1RAB9ATDP1 | |
| Benzene SCHEMBL27538848 | 0.75 | SMN1; SMN2 (0.44) | ALDH1A1HSD17B10P4HBKDM4ENPC1 | |
| SCHEMBL288904 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HSD17B10NAMPTNPC1RAB9A | |
| SCHEMBL197613 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HSD17B10PRMT5NAMPTL3MBTL1 | |
| SCHEMBL2088376 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HSD17B10PRMT5NAMPTP4HB | |
| SCHEMBL926998 | 0.72 | LMNA (0.46) | ALDH1A1HSD17B10NAMPTNPC1RAB9A | |
| SCHEMBL10883913 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HSD17B10PRMT5NAMPT | |
| SCHEMBL744132 | 0.72 | SMN1; SMN2 (0.46) | ALDH1A1HSD17B10P4HBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-B1 | HETEROCYCLICALLY SUBSTITUTED THIO(CYCLO)ALKANE POLYCARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |