Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.61 |
| ▸ | HTR3B | O95264 | 1/20 | 0.61 |
| ▸ | HTR3A | P46098 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.61 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.61 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305046 | 0.84 | F7 (0.44) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL1748354 | 0.79 | ALDH1A1 (0.66) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL29770331 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL2105330 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL2884316 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL9306275 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL6630362 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL9305169 | 0.76 | KMT2A (0.58) | ALDH1A1HPGDSMN1; SMN2TP53HSD17B10 | |
| SCHEMBL658809 | 0.76 | HTR3E (1.00) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL22962342 | 0.76 | HPGD (0.70) | ALDH1A1HTR3EHTR3BHTR3ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4585596-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | Shanghai Yingli Pharmaceutical Co., Ltd (CN) | 2025-07-16 | — | — | EP | disclosed |
| CN-118209665-A | High-efficiency liquid phase detection method for equine ribavirin | 南京海纳医药科技股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118209665-A | High-efficiency liquid phase detection method for equine ribavirin | 南京海纳医药科技股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-20240158408-A1 | Nitrogen-Containing Heterocyclic Compound, Pharmaceutical Compositions thereof and Use thereof | 280 BIO, INC. (US) | 2024-05-16 | — | — | US | disclosed |
| WO-2024051784-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 上海璎黎药业有限公司 | 2024-03-14 | — | — | WO | disclosed |
| CN-117683036-A | Nitrogen-containing heterocyclic compound, pharmaceutical composition and application thereof | 上海璎黎药业有限公司 | 2024-03-12 | — | — | CN | disclosed |
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158408-A1 | Nitrogen-Containing Heterocyclic Compound, Pharmaceutical Compositions thereof and Use thereof | MTOR, AKT1, AKT2 | ALDH1A1 3381/4885HTR3E 1886/4885HTR3B 1325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.