Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NSD2 | O96028 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27518334 | 0.76 | HSD11B1 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18689383 | 0.69 | HRH1 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7622505 | 0.67 | HRH1 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10446509 | 0.67 | TDP2 (0.73) | TDP2NPC1SMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL10386402 | 0.67 | NPC1 (0.58) | NPC1SMN1; SMN2RAB9AMAPK1TP53 | |
| SCHEMBL6509065 | 0.66 | PKM (0.60) | NPC1SMN1; SMN2RAB9APKMMAPT | |
| SCHEMBL28445132 | 0.66 | HRH1 (0.35) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9424119 | 0.65 | LMNA (0.62) | NPC1SMN1; SMN2RAB9ATSHRPKM | |
| SCHEMBL19628266 | 0.65 | APAF1 (0.64) | TDP2NPC1SMN1; SMN2RAB9AMAPK1 | |
| Ammonia Solution, Strong SCHEMBL28335510 | 0.65 | PKM (0.58) | NPC1SMN1; SMN2RAB9APKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292736-A | Morpholinoalkylindenes as antiglaucoma agents | STERLING WINTHROP INC. (US) | 1994-03-08 | — | — | US | disclosed |