Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021985 | 0.82 | CEPT1 (0.39) | KMT2APIK3CDPIK3CBALDH1A1LMNA | |
| SCHEMBL9306222 | 0.82 | DAGLA (0.43) | KMT2APIK3CDPIK3CBALDH1A1LMNA | |
| SCHEMBL9305342 | 0.81 | TOP2A (0.39) | TOP2APIK3CDPIK3CAPIK3CBLIPG | |
| SCHEMBL11020685 | 0.81 | LMNA (0.36) | KMT2AALDH1A1HSD17B10LMNAMAPK1 | |
| SCHEMBL8973074 | 0.80 | SOAT1 (0.36) | — | |
| SCHEMBL8972322 | 0.80 | RAB9A (0.43) | KMT2AALDH1A1MEN1MAPTGAA | |
| SCHEMBL9733955 | 0.79 | SMN1; SMN2 (0.32) | KMT2AALDH1A1MEN1 | |
| SCHEMBL9304101 | 0.79 | ALDH1A1 (0.31) | KMT2AALDH1A1 | |
| SCHEMBL9306332 | 0.79 | HSD17B10 (0.38) | KMT2AALDH1A1USP2HSD17B10MEN1 | |
| Ammonia Solution, Strong SCHEMBL10865667 | 0.79 | RAB9A (0.42) | KMT2AALDH1A1MEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |