Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823132 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10CYP3A4ALOX15 | |
| SCHEMBL3947426 | 0.86 | HSD17B10 (0.50) | ALDH1A1KDM4EHSD17B10CYP3A4ALOX15 | |
| SCHEMBL3897640 | 0.84 | CYP3A4 (0.65) | HSD17B10CYP3A4ALOX15KIF11 | |
| SCHEMBL23155928 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10CYP3A4ALOX15 | |
| SCHEMBL5958751 | 0.83 | HSD17B10 (0.46) | ALDH1A1KDM4EHSD17B10CYP3A4ALOX15 | |
| SCHEMBL29399630 | 0.83 | ESR1 (0.50) | ALDH1A1KDM4EHSD17B10CYP3A4ALOX15 | |
| SCHEMBL766058 | 0.83 | ESR1 (0.50) | ALDH1A1KDM4EHSD17B10CYP3A4ALOX15 | |
| SCHEMBL29412586 | 0.83 | ESR1 (0.50) | ALDH1A1KDM4EHSD17B10CYP3A4ALOX15 | |
| SCHEMBL1023841 | 0.82 | ALDH1A1 (0.63) | ALDH1A1KDM4EHSD17B10ALOX15HPGD | |
| SCHEMBL11371728 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1KDM4EHSD17B10CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118557555-B | Curcumin compound preparation and application thereof in treating MLL-r leukemia | 济宁医学院附属医院 | 2024-12-06 | — | — | CN | claimed |
| CN-118557555-A | Curcumin compound preparation and application thereof in treating MLL-r leukemia | 济宁医学院附属医院 | 2024-08-30 | — | — | CN | claimed |
| CN-108059600-B | Refining method of tetra (dimethylamino) titanium | 浙江博瑞电子科技有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-101253169-B | Substituted benzimidazoles and processes for their preparation | NOVARTIS AG | 2011-11-23 | — | — | CN | claimed |
| CN-101253168-A | Substituted benzimidazoles as kinase inhibitors | NOVARTIS AG (CH) | 2008-08-27 | — | — | CN | claimed |
| CN-101253169-A | Substituted benzimidazoles and processes for their preparation | NOVARTIS AG (CH) | 2008-08-27 | — | — | CN | claimed |
| US-7364881-B1 | Biological process for the conversion of nitroarenes to ortho-aminophenols using recombinant E. coli strains | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2008-04-29 | — | — | US | claimed |
| US-12600720-B2 | Modulators of the integrated stress response pathway | EVOTEC INTERNATIONAL GMBH (DE) | 2026-04-14 | — | — | US | disclosed |
| US-20260022122-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | CHECKMATE THERAPEUTICS INC. (KR) | 2026-01-22 | — | — | US | disclosed |
| EP-4619388-A1 | CATHEPSIN L INHIBITORS | Biofront Therapeutics (Beijing) Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |
| EP-4583870-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | Mito Biopharma, LLC (US) | 2025-07-16 | — | — | EP | disclosed |
| CN-119775261-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2025-04-08 | — | — | CN | disclosed |
| EP-4487849-A2 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | Evotec International GmbH (DE) | 2025-01-08 | — | — | EP | disclosed |
| US-5780483-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-14 | — | — | US | disclosed |
| EP-0809492-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1997029743-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-21 | — | — | WO | disclosed |
| WO-1996025157-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-22 | — | — | WO | disclosed |
| US-4731450-A | Process for perfluoroalkylation of aromatic derivatives | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-03-15 | — | — | US | disclosed |
| US-4263441-A | BENZOXAZOLE DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-04-21 | — | — | US | disclosed |
| EP-0002030-A1 | Fluorinated benzazole derivatives, method for their preparation and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12600720-B2 | Modulators of the integrated stress response pathway | CRHR2, CRHR1, MC2R | ALDH1A1 3637/4885KDM4E 4082/4885HSD17B10 2345/4885 |
| US-20260022122-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | NAMPT, NAPRT, NNT | ALDH1A1 789/4885KDM4E 2601/4885HSD17B10 473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.