Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.31 |
| ▸ | HPGD | P15428 | 6/20 | 0.31 |
| ▸ | GAA | P10253 | 5/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305543 | 0.82 | KMT2A (0.43) | MEN1KMT2AALDH1A1CTRCTLR8 | |
| SCHEMBL21066316 | 0.75 | AHR (0.39) | ALDH1A1ESR1ESR2MAPK1MAPT | |
| SCHEMBL10879283 | 0.74 | GAA (0.33) | MEN1KMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL11572467 | 0.73 | AHR (0.38) | ALDH1A1ESR1ESR2MAPK1MAPT | |
| SCHEMBL9306655 | 0.73 | MEN1 (0.37) | MEN1KMT2AALDH1A1EIF4A1KDM4E | |
| SCHEMBL6010846 | 0.73 | LMNA (0.38) | KMT2AALDH1A1ESR1ESR2KDM4E | |
| SCHEMBL8359245 | 0.71 | CTRC (0.44) | MEN1KMT2AALDH1A1CTRCTLR8 | |
| SCHEMBL9305797 | 0.71 | CASP3 (0.36) | MEN1KMT2AALDH1A1TLR8KDM4E | |
| SCHEMBL9306048 | 0.71 | GAA (0.43) | MEN1KMT2ATLR8GAAHTT | |
| SCHEMBL16391572 | 0.70 | PGK1 (0.44) | GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |