SCHEMBL9305978

SCHEMBL9305978

Cc1cc(C)c(O)c(Cc2cc(C(c3ccccc3)c3cc(Cc4cc(C)cc(C)c4O)c(O)c(Cc4cc(C)cc(C)c4O)c3)cc(Cc3cc(C)cc(C)c3O)c2O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.46
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
HIF1A Q16665 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSPA5 P11021 1/20 0.39
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
EGFR P00533 4/20 0.38
ERBB2 P04626 3/20 0.38
CYP2D6 P10635 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HKDC1 Q2TB90 1/20 0.34
ALDH1A1 P00352 3/20 0.33
GAA P10253 3/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MASP2 O00187 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9305110 0.84 AMY1A (0.66) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL30374837 0.80 AMY1A (0.61) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL4456468 0.80 AMY1A (0.61) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL30669854 0.80 AMY1A (0.61) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL15105759 0.80 AMY1A (0.61) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL27049069 0.78 TACR1 (0.37) AMY1ASLC6A2SLC6A4SLC6A3HSD17B10
SCHEMBL69707 0.78 AMY1A (0.57) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL22238269 0.77 ALOX5 (0.43) SLC6A2SLC6A4SLC6A3HKDC1ALDH1A1
SCHEMBL544660 0.77 BCL2 (0.52) AMY1AEGFRERBB2ALOX5
SCHEMBL2026462 0.76 PTGS1 (0.48) SLC6A2SLC6A4SLC6A3HKDC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5376498-A Blend of an alkali-soluble resin, compound that generates an acid upon irradiation, functional aromatic compound and a phenolic compound JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-12-27 US disclosed
EP-0542572-A1 Negative type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-05-19 EP disclosed