Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15325112 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL14967504 | 0.80 | TSHR (0.44) | ALDH1A1MEN1PPARGKMT2ASMN1; SMN2 | |
| SCHEMBL12518968 | 0.75 | PGD (0.42) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL2225864 | 0.75 | PGD (0.42) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL16488727 | 0.73 | TSHR (0.39) | ALDH1A1KMT2ATSHRL3MBTL1MAPK1 | |
| SCHEMBL16421028 | 0.73 | TSHR (0.39) | ALDH1A1KMT2ATSHRL3MBTL1MAPK1 | |
| SCHEMBL16421031 | 0.73 | TSHR (0.39) | ALDH1A1KMT2ATSHRL3MBTL1MAPK1 | |
| SCHEMBL14967607 | 0.72 | L3MBTL1 (0.43) | ALDH1A1POLBL3MBTL1ELANEGAA | |
| SCHEMBL9134240 | 0.72 | TSHR (0.42) | ALDH1A1MEN1PPARGKMT2ASMN1; SMN2 | |
| SCHEMBL14967425 | 0.72 | POLB (0.40) | ALDH1A1TSHRCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328638-A | Increasing spontaneous polarization | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |