SCHEMBL14967607

SCHEMBL14967607

CCC1OC1(C)C(=O)Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.43
POLB P06746 1/20 0.43
ATM Q13315 2/20 0.36
ELANE P08246 2/20 0.36
MAPT P10636 3/20 0.36
TDP1 Q9NUW8 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
RAB9A P51151 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP19A1 P11511 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14966775 0.80 L3MBTL1 (0.47) L3MBTL1POLBATMELANEMAPT
SCHEMBL14967532 0.80 POLB (0.39) L3MBTL1POLBATMELANEMAPT
SCHEMBL14966796 0.76 L3MBTL1 (0.43) L3MBTL1POLBATMELANEMAPT
SCHEMBL14967898 0.73 MAPT (0.39) L3MBTL1POLBELANEMAPTTDP1
SCHEMBL9306821 0.72 ALDH1A1 (0.40) L3MBTL1POLBELANEMAPTGAA
SCHEMBL16109082 0.72 USP2 (0.42) L3MBTL1POLBMAPTKDM4EALDH1A1
SCHEMBL14967580 0.71 EDNRA (0.43) L3MBTL1POLBMAPTGAAALDH1A1
SCHEMBL14967920 0.69 L3MBTL1 (0.49) L3MBTL1POLBATMELANEMAPT
SCHEMBL14967334 0.69 USP2 (0.39) L3MBTL1POLBMAPTGAA
SCHEMBL14967425 0.69 POLB (0.40) L3MBTL1POLBELANEMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed