Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306632 | 0.81 | KMT2A (0.37) | MEN1KMT2ASMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL2748445 | 0.72 | PSMB8 (0.40) | MEN1KMT2ASMN1; SMN2LMNAELANE | |
| SCHEMBL1851438 | 0.71 | PSMB8 (0.59) | MEN1KMT2ASMN1; SMN2CYP3A4LMNA | |
| SCHEMBL9304750 | 0.71 | CTRC (0.45) | CTRCMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL213846 | 0.70 | DHFR (0.46) | MEN1KMT2ASMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL10341448 | 0.70 | MET (0.50) | MEN1KMT2ASMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL29501702 | 0.70 | MET (0.50) | MEN1KMT2ASMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL9305900 | 0.70 | APP (0.46) | KMT2ASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11403614 | 0.68 | CALM1 (0.52) | CTRCMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL20969721 | 0.68 | KDM4E (0.42) | MEN1KMT2ASMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-B1 | HETEROCYCLICALLY SUBSTITUTED THIO(CYCLO)ALKANE POLYCARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |