Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139136 | 0.93 | FFAR1 (0.46) | PTGER2ALDH1A1POLBP2RY2LTB4R | |
| SCHEMBL6138878 | 0.93 | FFAR1 (0.46) | PTGER2ALDH1A1POLBP2RY2LTB4R | |
| SCHEMBL6138383 | 0.93 | FFAR1 (0.46) | PTGER2ALDH1A1POLBP2RY2LTB4R | |
| SCHEMBL2743391 | 0.93 | ALDH1A1 (0.49) | PTGER2ALDH1A1POLBP2RY2TBXAS1 | |
| SCHEMBL7115734 | 0.87 | GABBR2 (0.47) | ALDH1A1POLB | |
| SCHEMBL6907990 | 0.84 | TBXAS1 (0.58) | LTB4RTBXAS1 | |
| SCHEMBL9308449 | 0.84 | TBXAS1 (0.58) | LTB4RTBXAS1 | |
| SCHEMBL6907995 | 0.84 | TBXAS1 (0.58) | LTB4RTBXAS1 | |
| SCHEMBL8742992 | 0.83 | TBXA2R (0.58) | PTGER2LTB4RPTGER4PTGER3 | |
| SCHEMBL4427857 | 0.83 | FFAR1 (0.48) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | disclosed |