Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393806 | 0.79 | CYP11B1 (0.42) | CYP11B1CYP11B2GABRG2GABRB3GABRA5 | |
| SCHEMBL9308663 | 0.79 | ALOX5 (0.48) | CYP2D6 | |
| SCHEMBL9308523 | 0.77 | ALOX5 (0.62) | CYP2D6 | |
| SCHEMBL9308680 | 0.76 | ALOX5 (0.52) | CYP2D6 | |
| SCHEMBL9308712 | 0.73 | ALOX5 (0.43) | GPR84CYP2D6 | |
| SCHEMBL30293242 | 0.73 | SRD5A1 (0.60) | CYP11B1CYP11B2GABRG2GABRB3GABRA5 | |
| SCHEMBL9309603 | 0.73 | ALOX5 (0.60) | CYP2D6 | |
| SCHEMBL8953851 | 0.72 | SLC2A1 (0.43) | CYP2D6 | |
| SCHEMBL9309282 | 0.68 | ALOX5 (0.48) | CYP2D6 | |
| SCHEMBL9210905 | 0.67 | ALOX5 (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |