Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309603 | 0.95 | ALOX5 (0.60) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9308141 | 0.86 | ALOX5 (0.47) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9308663 | 0.85 | ALOX5 (0.48) | ALOX5CYP2D6 | |
| SCHEMBL9308680 | 0.83 | ALOX5 (0.52) | ALOX5CYP2D6 | |
| SCHEMBL9307254 | 0.81 | ALOX5 (0.64) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9139351 | 0.77 | ALOX5 (1.00) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9307970 | 0.77 | CYP11B1 (0.42) | CYP2D6 | |
| SCHEMBL9209013 | 0.76 | ALOX5 (0.81) | ALOX5 | |
| SCHEMBL9136256 | 0.76 | ALOX5 (0.57) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9309991 | 0.76 | ALOX5 (0.46) | ALOX5CYP2D6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |