Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.41 |
| ▸ | USP1 | O94782 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308523 | 0.85 | ALOX5 (0.62) | ALOX5CYP2D6 | |
| SCHEMBL9309603 | 0.81 | ALOX5 (0.60) | ALOX5CYP2D6 | |
| SCHEMBL9307970 | 0.79 | CYP11B1 (0.42) | CYP2D6 | |
| SCHEMBL9308680 | 0.79 | ALOX5 (0.52) | ALOX5CYP2D6PRKDC | |
| SCHEMBL9390739 | 0.78 | ALOX5 (0.48) | ALOX5TRIM24PRKDC | |
| SCHEMBL9308712 | 0.76 | ALOX5 (0.43) | ALOX5CYP2D6SLC2A1 | |
| SCHEMBL8953851 | 0.75 | SLC2A1 (0.43) | CYP2D6CNR1CNR2SLC2A1MAOB | |
| SCHEMBL9308141 | 0.74 | ALOX5 (0.47) | ALOX5CYP2D6USP1 | |
| SCHEMBL9309282 | 0.71 | ALOX5 (0.48) | ALOX5CYP2D6PRKDC | |
| SCHEMBL13097002 | 0.69 | MAOB (0.47) | CYP2D6CNR1CNR2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |