Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308680 | 0.91 | ALOX5 (0.52) | ALOX5PRKDCCYP2D6 | |
| SCHEMBL13097002 | 0.79 | MAOB (0.47) | CYP4F2CYP4A11CYP2D6 | |
| SCHEMBL9308599 | 0.79 | ALOX5 (0.45) | ALOX5PRKDCCYP2D6 | |
| SCHEMBL9308523 | 0.75 | ALOX5 (0.62) | ALOX5CYP2D6 | |
| SCHEMBL9308712 | 0.75 | ALOX5 (0.43) | ALOX5CYP2D6 | |
| SCHEMBL9308988 | 0.75 | ALOX5 (0.35) | ALOX5CYP2D6 | |
| SCHEMBL9310099 | 0.74 | ALOX5 (0.48) | ALOX5PRKDC | |
| SCHEMBL9309603 | 0.73 | ALOX5 (0.60) | ALOX5CYP2D6 | |
| SCHEMBL9308093 | 0.72 | MRGPRX4 (0.51) | ALOX5 | |
| SCHEMBL16150040 | 0.71 | SLC2A1 (0.49) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994005281-A1 | PHENYLMETHYL DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |