Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 0.52 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309282 | 0.91 | ALOX5 (0.48) | ALOX5PRKDCCYP2D6 | |
| SCHEMBL9308599 | 0.83 | ALOX5 (0.45) | ALOX5PRKDCCYP2D6 | |
| SCHEMBL9308712 | 0.83 | ALOX5 (0.43) | ALOX5CYP2D6 | |
| SCHEMBL9308988 | 0.83 | ALOX5 (0.35) | ALOX5CYP2D6 | |
| SCHEMBL9308523 | 0.83 | ALOX5 (0.62) | ALOX5CYP2D6 | |
| SCHEMBL9308663 | 0.79 | ALOX5 (0.48) | ALOX5PRKDCCYP2D6 | |
| SCHEMBL9309603 | 0.78 | ALOX5 (0.60) | ALOX5CYP2D6 | |
| SCHEMBL13097002 | 0.78 | MAOB (0.47) | CYP2D6 | |
| SCHEMBL8953851 | 0.78 | SLC2A1 (0.43) | CYP2D6 | |
| SCHEMBL9310099 | 0.77 | ALOX5 (0.48) | ALOX5PRKDCTLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994005281-A1 | PHENYLMETHYL DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |