⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27640435 | 0.98 | RAB9A (0.36) | — | |
| SCHEMBL28733761 | 0.98 | RAB9A (0.36) | — | |
| SCHEMBL23365328 | 0.83 | HTR2A (0.39) | — | |
| SCHEMBL8422 | 0.82 | — | — | |
| SCHEMBL27563324 | 0.80 | TDP1 (0.36) | — | |
| SCHEMBL8674 | 0.78 | CA2 (0.46) | — | |
| SCHEMBL28367075 | 0.78 | TDP1 (0.33) | — | |
| SCHEMBL161774 | 0.77 | L3MBTL1 (0.46) | — | |
| SCHEMBL542967 | 0.77 | TRPV3 (0.31) | — | |
| SCHEMBL21268193 | 0.77 | L3MBTL1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3557 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307569-A | 2-Aryl-4-boron heterocyclic compound, and stereoselective preparation method and application thereof | 武汉大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118206551-A | Quinoline compounds, their preparation and their use as antimalarial agents | 美国卫生和人力服务部 | 2024-06-18 | — | — | CN | claimed |
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | claimed |
| US-20240174603-A1 | MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | RAPPTA THERAPEUTICS OY (FI) | 2024-05-30 | — | — | US | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| US-RE49934-E1 | Inhibitors of cellular metabolic processes | SERVIER PHARMACEUTICALS LLC (US) | 2024-04-23 | — | — | US | claimed |
| EP-3893645-B1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2024-04-17 | — | — | EP | claimed |
| WO-2024073283-A1 | HETEROCYCLES AS MODULATORS OF NSD ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-04-04 | — | — | WO | claimed |
| WO-2024073282-A2 | HETEROCYCLES AS MODULATORS OF NSD ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-04-04 | — | — | WO | claimed |
| EP-4288412-A1 | MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | Rappta Therapeutics Oy (FI) | 2023-12-13 | — | — | EP | claimed |
| CN-1094613-A | Novel therapeutic agents | SMITHKLINE BEECHAM PLC (GB) | 1994-11-09 | — | — | CN | claimed |
| EP-0619806-A1 | PREPARATION OF SUBSTITUTED PIPERIDINES. | PFIZER (US) | 1994-10-19 | — | — | EP | claimed |
| US-5326781-A | Benzylimidazole derivatives as anxiolytic agents and cognition activators | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1994-07-05 | — | — | US | claimed |
| WO-1994013656-A1 | BICYCLIC COMPOUNDS WITH PHARMACEUTICAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-06-23 | — | — | WO | claimed |
| US-5231105-A | Ethylamine derivatives and antihypertensives containing the same | AJINOMOTO CO., INC. (JP) | 1993-07-27 | — | — | US | claimed |
| WO-1993011110-A1 | PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1993-06-10 | — | — | WO | claimed |
| EP-0527869-A1 | BENZYLIMIDAZOLE DERIVATIVES AS ANXIOLYTIC AND NOOTROPIC AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-02-24 | — | — | EP | claimed |
| WO-1991016890-A1 | BENZYLIMIDAZOLE DERIVATIVES AS ANXIOLYTIC AND NOOTROPIC AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-14 | — | — | WO | claimed |
| EP-0141909-A2 | E-Triazolylpentenols, process for their preparation and biocides and plant growth regulators containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-05-22 | — | — | EP | claimed |
| EP-0134515-A1 | Azolyl-propane nitriles, method for the preparation of these compounds and biocide agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | claimed |