Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151441 | 0.85 | AKR1C4 (0.33) | MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL9151445 | 0.85 | AKR1C4 (0.33) | MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7318335 | 0.77 | KDM4E (0.39) | OPRK1SERPINH1MEN1KMT2AABL1 | |
| SCHEMBL7317477 | 0.77 | KDM4E (0.39) | OPRK1SERPINH1MEN1KMT2AABL1 | |
| SCHEMBL7311217 | 0.77 | KDM4E (0.39) | OPRK1SERPINH1MEN1KMT2AABL1 | |
| SCHEMBL7414700 | 0.71 | SLC6A3 (0.38) | OPRK1SERPINH1MEN1KMT2AABL1 | |
| SCHEMBL7414698 | 0.71 | SLC6A3 (0.38) | OPRK1SERPINH1MEN1KMT2AABL1 | |
| SCHEMBL12036045 | 0.68 | PARP1 (0.48) | SERPINH1MEN1KMT2AABL1SIRT2 | |
| SCHEMBL7399556 | 0.67 | LMNA (0.38) | OPRK1SERPINH1MEN1KMT2AABL1 | |
| SCHEMBL8364696 | 0.65 | HTR3A (0.50) | SERPINH1ABL1SLC6A3SLC6A4HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278323-A | Process for preparing chiral dibenzofurans via intramolecular heck reaction | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-01-11 | — | — | US | claimed |
| US-5278323-A | Process for preparing chiral dibenzofurans via intramolecular heck reaction | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-01-11 | — | — | US | disclosed |