Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414700 | 1.00 | SLC6A3 (0.38) | SLC6A3PTGDRPTGDR2OPRK1SERPINH1 | |
| SCHEMBL7413425 | 0.84 | HSD17B10 (0.36) | PTGDRPTGDR2KDM4EALDH1A1HPGD | |
| SCHEMBL7410883 | 0.84 | HSD17B10 (0.36) | PTGDRPTGDR2KDM4EALDH1A1HPGD | |
| SCHEMBL7424445 | 0.84 | HSD17B10 (0.36) | PTGDRPTGDR2KDM4EALDH1A1HPGD | |
| SCHEMBL7317482 | 0.76 | KDM4E (0.39) | SLC6A3PTGDRPTGDR2OPRK1SERPINH1 | |
| SCHEMBL7318335 | 0.76 | KDM4E (0.39) | SLC6A3PTGDRPTGDR2OPRK1SERPINH1 | |
| SCHEMBL7317477 | 0.76 | KDM4E (0.39) | SLC6A3PTGDRPTGDR2OPRK1SERPINH1 | |
| SCHEMBL7311217 | 0.76 | KDM4E (0.39) | SLC6A3PTGDRPTGDR2OPRK1SERPINH1 | |
| SCHEMBL9509199 | 0.74 | HTR3A (0.58) | ALDH1A1 | |
| SCHEMBL9309022 | 0.71 | OPRK1 (0.34) | SLC6A3OPRK1SERPINH1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288731-A | Antiemetics, antiserotonine agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-02-22 | — | — | US | disclosed |
| EP-0559656-A1 | PROCESS FOR PREPARING MULTICYCLIC OXY-CONTAINING RING COMPONENTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009592-A1 | PROCESS FOR PREPARING MULTICYCLIC OXY-CONTAINING RING COMPONENTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-06-11 | — | — | WO | disclosed |
| WO-1992009284-A1 | 2,6-METHANO-2H-1-BENZOXOCINCARBOXAMIDES AS 5-HT3-ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-06-11 | — | — | WO | disclosed |