Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310260 | 0.86 | LMNA (0.50) | KMT2ALMNAGAAALDH1A1HPGD | |
| SCHEMBL10006897 | 0.82 | LTA4H (0.55) | KMT2ALMNAGAAALDH1A1TTR | |
| SCHEMBL895837 | 0.77 | TTR (0.41) | KMT2ALMNAGAAALDH1A1HPGD | |
| SCHEMBL9309726 | 0.76 | LMNA (0.40) | KMT2ALMNAGAAALDH1A1HPGD | |
| SCHEMBL12792086 | 0.75 | HTT (0.53) | KMT2ALMNAALDH1A1LTA4HTSHR | |
| SCHEMBL9311231 | 0.75 | ALDH1A1 (0.37) | KMT2AGAAALDH1A1TSHRKDM4E | |
| SCHEMBL8736795 | 0.75 | LTA4H (0.46) | KMT2ALMNAGAAALDH1A1TTR | |
| SCHEMBL298766 | 0.75 | LMNA (0.64) | KMT2ALMNAGAAALDH1A1HPGD | |
| SCHEMBL30618855 | 0.75 | LMNA (0.64) | KMT2ALMNAGAAALDH1A1HPGD | |
| SCHEMBL8150678 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326489-A | Sulfonated polymer | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0523300-B1 | Electrorheological fluids | NIPPON CATALYTIC CHEM IND (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0523300-A1 | Electrorheological fluids | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |