Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | SREBF2 | Q12772 | 5/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070549 | 0.83 | — | — | |
| SCHEMBL1128418 | 0.83 | NOS3 (0.42) | NOS2NOS3SREBF2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13026558 | 0.78 | NOS2 (0.48) | NOS2NOS3NOS1SREBF2BACE1 | |
| SCHEMBL21090979 | 0.78 | NOS2 (0.48) | NOS2NOS3NOS1SREBF2BACE1 | |
| SCHEMBL30227466 | 0.78 | NOS2 (0.48) | NOS2NOS3NOS1SREBF2BACE1 | |
| Propylthiouracil SCHEMBL4446870 | 0.78 | SREBF2 (0.42) | NOS2NOS3NOS1SREBF2BACE1 | |
| SCHEMBL13153625 | 0.78 | NOS2 (0.48) | NOS2NOS3NOS1SREBF2BACE1 | |
| SCHEMBL8545461 | 0.77 | SMN1; SMN2 (0.41) | ALDH1A1KDM4ESMN1; SMN2 | |
| Propylthiouracil SCHEMBL11615920 | 0.76 | NOS3 (0.39) | NOS2NOS3NOS1SREBF2BACE1 | |
| Propylthiouracil SCHEMBL5548120 | 0.76 | SREBF2 (0.41) | NOS2NOS3NOS1SREBF2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080193397-A1 | Use of Peroxide Decomposers Method For the Treatment of a Material Other Than the Human Body | BASF AKTIENGESELLSCAFT (DE) | 2008-08-14 | — | — | US | disclosed |
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080193397-A1 | Use of Peroxide Decomposers Method For the Treatment of a Material Other Than the Human Body | GPX4, LPO, GPX1 | NOS2 314/4885NOS3 354/4885NOS1 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.