Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5427807 | 0.83 | — | — | |
| SCHEMBL21083750 | 0.77 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL21083543 | 0.76 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL21083569 | 0.76 | AGTR2 (0.74) | AGTR1AGTR2 | |
| SCHEMBL9140759 | 0.76 | SMN1; SMN2 (0.64) | — | |
| SCHEMBL7014233 | 0.75 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL14610985 | 0.75 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9347486 | 0.75 | PKM (0.43) | AGTR1 | |
| L-158809 SCHEMBL683357 | 0.75 | AGTR2 (0.71) | AGTR1AGTR2 | |
| SCHEMBL8843709 | 0.75 | AGTR1 (0.68) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334718-A | Decyclizing a phenyl or a pyridyl or pyrimidyl group by reacting with a base to get angiotension antagonist | ZENECA LIMITED (GB) | 1994-08-02 | — | — | US | disclosed |
| EP-0554098-A2 | Process for the preparation of imidazo 4,5-b pyridine derivatives | ZENECA LIMITED (GB) | 1993-08-04 | — | — | EP | disclosed |