Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL816365 | 0.95 | CYP19A1 (0.48) | CYP19A1LMNATSHRVCAM1CYP3A4 | |
| SCHEMBL15545359 | 0.87 | CYP19A1 (0.41) | CYP19A1LMNATSHRVCAM1CYP3A4 | |
| SCHEMBL15544726 | 0.86 | CYP19A1 (0.40) | CYP19A1LMNATSHRVCAM1CYP3A4 | |
| SCHEMBL6863360 | 0.84 | ALDH1A1 (0.46) | CYP19A1TSHRCYP3A4ALDH1A1HIF1A | |
| SCHEMBL28967021 | 0.82 | XDH (0.39) | CYP19A1LMNATSHRVCAM1ALDH1A1 | |
| SCHEMBL28967049 | 0.82 | CYP3A4 (0.47) | CYP19A1LMNATSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL29985009 | 0.81 | TP53 (0.50) | LMNATSHRCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL14793406 | 0.81 | TSHR (0.37) | CYP19A1LMNATSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL1169028 | 0.81 | TP53 (0.50) | LMNATSHRCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL212845 | 0.79 | CYP19A1 (0.81) | CYP19A1LMNATSHRVCAM1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110301382-A1 | Processes for Preparing 1,3-Dinitro-5-(Pentafluorosulfanyl)Benzene and its Intermediates | UBE INDUSTRIES, LTD. (JP) | 2011-12-08 | — | — | US | claimed |
| US-20160096852-A1 | Synthesis of 4-(pentafluorosulfanyl)benzenediazonium tetrafluoroborate and Analogs | UNIVERSITY OF NORTH FLORIDA (US) | 2016-04-07 | — | — | US | disclosed |
| US-9284336-B1 | Synthesis of 4-(pentafluorosulfanyl)benzenediazonium tetrafluoroborate and analogs | UNIVERSITY OF NORTH FLORIDA (US) | 2016-03-15 | — | — | US | disclosed |
| US-9238660-B1 | Synthesis of 4-(pentafluorosulfanyl)benzenediazonium tetrafluoroborate and analogs and their application for the preparation of SF5-aromatics | UNIVERSITY OF NORTH FLORIDA (US) | 2016-01-19 | — | — | US | disclosed |
| US-20110301382-A1 | Processes for Preparing 1,3-Dinitro-5-(Pentafluorosulfanyl)Benzene and its Intermediates | UBE INDUSTRIES, LTD. (JP) | 2011-12-08 | — | — | US | disclosed |
| US-20110301382-A1 | Processes for Preparing 1,3-Dinitro-5-(Pentafluorosulfanyl)Benzene and its Intermediates | UBE INDUSTRIES, LTD. (JP) | 2011-12-08 | — | — | US | disclosed |
| US-20110301382-A1 | Processes for Preparing 1,3-Dinitro-5-(Pentafluorosulfanyl)Benzene and its Intermediates | UBE INDUSTRIES, LTD. (JP) | 2011-12-08 | — | — | US | disclosed |
| US-20110301382-A1 | Processes for Preparing 1,3-Dinitro-5-(Pentafluorosulfanyl)Benzene and its Intermediates | UBE INDUSTRIES, LTD. (JP) | 2011-12-08 | — | — | US | disclosed |
| US-5302692-A | High glass transition temperature, low dielectric properties | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINSTRATION (US) | 1994-04-12 | — | — | US | disclosed |
| US-5220070-A | 1,3-diamino-5-pentafluorosulfanylbenzene | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1993-06-15 | — | — | US | disclosed |
| US-5220070-A | 1,3-diamino-5-pentafluorosulfanylbenzene | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1993-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096852-A1 | Synthesis of 4-(pentafluorosulfanyl)benzenediazonium tetrafluoroborate and Analogs | HCK, NEK5, SIK2 | CYP19A1 4438/4885LMNA 4811/4885TSHR 1493/4885 |
| US-20110301382-A1 | Processes for Preparing 1,3-Dinitro-5-(Pentafluorosulfanyl)Benzene and its Intermediates | DPYD, FDPS, BLVRB | CYP19A1 2203/4885LMNA 3222/4885TSHR 3083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.