Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24844736 | 0.91 | GAA (0.76) | GAALMNAL3MBTL1TDP1NPC1 | |
| SCHEMBL18879750 | 0.82 | IDO1 (0.43) | GAALMNATDP1 | |
| SCHEMBL16270511 | 0.82 | GAA (0.59) | GAALMNAL3MBTL1TDP1NPC1 | |
| SCHEMBL7068289 | 0.82 | LMNA (0.59) | GAALMNAL3MBTL1TDP1NPC1 | |
| SCHEMBL197602 | 0.82 | PTGS2 (0.58) | GAALMNAL3MBTL1 | |
| SCHEMBL472034 | 0.81 | ALOX15 (0.65) | GAALMNAL3MBTL1TDP1NPC1 | |
| SCHEMBL689763 | 0.80 | KMT2A (0.54) | GAALMNATDP1 | |
| SCHEMBL689206 | 0.80 | KMT2A (0.65) | GAALMNATDP1 | |
| SCHEMBL13266603 | 0.79 | KMT2A (0.40) | GAALMNATDP1 | |
| SCHEMBL8068275 | 0.79 | LMNA (0.44) | GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286881-A | Reacting substituted hydroxy benzofuranone with acetonitrile compound in presence of acid catalyst, oxidizing | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-02-15 | — | — | US | disclosed |