Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313658 | 0.84 | ACHE (0.47) | LMNAALDH1A1TDP1ABCB1SMN1; SMN2 | |
| SCHEMBL9313579 | 0.79 | ALDH1A1 (0.61) | FAAHMGLLLMNAALDH1A1CYP1A2 | |
| SCHEMBL9312727 | 0.75 | CRHBP (0.46) | LMNAALDH1A1CYP2D6CYP2C19TDP1 | |
| SCHEMBL12895484 | 0.74 | ATM (0.46) | LMNAALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11026162 | 0.73 | ALDH1A1 (0.56) | LMNAALDH1A1CYP1A2MAPTTDP1 | |
| SCHEMBL5281104 | 0.72 | ALDH1A1 (0.53) | FAAHMGLLLMNAALDH1A1CYP1A2 | |
| SCHEMBL5281106 | 0.72 | MAPT (0.62) | FAAHMGLLLMNAALDH1A1CYP1A2 | |
| SCHEMBL11028205 | 0.72 | ALDH1A1 (0.63) | LMNAALDH1A1CYP1A2MAPTTDP1 | |
| SCHEMBL7096253 | 0.72 | ATM (0.49) | LMNAALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7202690 | 0.71 | TSHR (0.53) | LMNAALDH1A1CYP1A2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334710-A | Monomeric or polymeric compounds | SANDOZ LTD. (CH) | 1994-08-02 | — | — | US | disclosed |