Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315345 | 0.81 | ESR1 (0.41) | ESR1CA12CA1CA7CA9 | |
| SCHEMBL9315235 | 0.73 | BCHE (0.35) | ALOX5ESR1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL18152141 | 0.73 | SCN5A (0.46) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL11131743 | 0.72 | NQO1 (0.46) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL30648016 | 0.70 | EIF4A3 (0.37) | ESR1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL4429156 | 0.70 | KDM4E (0.44) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL2187802 | 0.68 | IDO1 (0.43) | ALOX5ESR1CA12CA1CA2 | |
| SCHEMBL30220176 | 0.68 | IDO1 (0.43) | ALOX5ESR1CA12CA1CA2 | |
| SCHEMBL9354906 | 0.68 | DAO (0.33) | ESR1KDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL27051592 | 0.68 | TRPA1 (0.33) | ALOX5ESR1KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354870-A | Hair dyes | L'OREAL (FR) | 1994-10-11 | — | — | US | disclosed |
| US-5131911-A | Hair dyes | L'OREAL (FR) | 1992-07-21 | — | — | US | disclosed |