Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315323 | 0.81 | ALOX5 (0.37) | ESR1CA12CA1CA7CA9 | |
| SCHEMBL9315240 | 0.77 | HPGD (0.61) | CA12CA1CA7CA9CA13 | |
| SCHEMBL9350768 | 0.75 | MCL1 (0.40) | AXLGAAKDM4EALDH1A1LMNA | |
| SCHEMBL9350909 | 0.75 | ALDH1A1 (0.53) | ESR1CA12CA1CA7CA9 | |
| SCHEMBL30648016 | 0.74 | EIF4A3 (0.37) | ESR1ESR2AXLGAAMGAM | |
| SCHEMBL4429156 | 0.73 | KDM4E (0.44) | CA12CA1CA9AXLGAA | |
| SCHEMBL27051592 | 0.71 | TRPA1 (0.33) | ESR1ESR2PPARGGAATDP1 | |
| SCHEMBL9354906 | 0.71 | DAO (0.33) | ESR1ESR2GAATDP1KDM4E | |
| SCHEMBL1880644 | 0.70 | CA1 (0.42) | ESR1ESR2CA12CA1CA7 | |
| SCHEMBL13344922 | 0.70 | KDM4E (0.58) | CA12CA1CA7CA9CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| US-5354870-A | Hair dyes | L'OREAL (FR) | 1994-10-11 | — | — | US | disclosed |
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | disclosed |
| US-5131911-A | Hair dyes | L'OREAL (FR) | 1992-07-21 | — | — | US | disclosed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |