Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4918625 | 1.00 | CA2 (0.36) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL5206344 | 0.77 | — | — | |
| SCHEMBL9315228 | 0.75 | THRB (0.31) | LMNATHRB | |
| SCHEMBL3175635 | 0.75 | THRB (0.31) | LMNATHRB | |
| SCHEMBL19210097 | 0.74 | LMNA (0.33) | LMNA | |
| SCHEMBL21633726 | 0.69 | THRB (0.43) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL21633789 | 0.69 | THRB (0.43) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL187513 | 0.69 | THRB (0.43) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL9778150 | 0.69 | THRB (0.43) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL28881707 | 0.69 | THRB (0.43) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306615-A | Liquid perfluorocarbon support; fluorinated isocyanate anchor groups | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5276146-A | Ligand attached to support with isocyanate anchor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| US-5268456-A | Immobilizing a protein; bonding to ligand | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| US-5268307-A | Dissolving a perfluoroisocyanate emulsifier with ligand or binder | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| EP-0281368-B1 | ENZYME IMMOBILIZATION AND BIOAFFINITY SEPARATIONS WITH PERFLUOROCARBON POLYMER-BASED SUPPORTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0246103-B1 | BIOAFFINITY AND ION EXCHANGE SEPARATIONS WITH LIQUID EXCHANGE SUPPORTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-25 | — | — | EP | disclosed |
| US-5158880-A | PROCESS FOR PREPARING SOLID PERFLUOROCARBON POLYMER SUPPORTS HAVING ATTACHED PERFLUOROCARBON-SUBSTITUTED LIGAND OR BINDER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0363052-B1 | PROCESS FOR PREPARING SOLID PERFLUOROCARBON POLYMER SUPPORTS HAVING ATTACHED PERFLUOROCARBON-SUBSTITUTED LIGAND OR BINDER | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4954444-A | Fluorinated isocyanate anchor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0363052-A1 | Process for preparing solid perfluorocarbon polymer supports having attached perfluorocarbon-substituted ligand or binder | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-11 | — | — | EP | disclosed |
| US-4885250-A | FOR COLORIMETRIC AND/OR QUANTITATIVE ANALYSIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0281368-A2 | Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-07 | — | — | EP | disclosed |
| EP-0246103-A2 | Bioaffinity and ion exchange separations with liquid exchange supports | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |