Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adamantane SCHEMBL851674 | 0.87 | CYP2C9 (0.41) | HSD11B1TSHRCYP2C9EPHX1EPHX2 | |
| Adamantane SCHEMBL935449 | 0.87 | HSD11B1 (0.48) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL974954 | 0.87 | HSD11B1 (0.48) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL3981833 | 0.87 | HSD11B1 (0.48) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL28221509 | 0.83 | HSD11B1 (0.46) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL27604496 | 0.82 | CYP2C9 (0.50) | HSD11B1TSHRCYP2C9LMNATHRB | |
| Adamantane SCHEMBL8402827 | 0.80 | FFAR3 (0.54) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL3098060 | 0.80 | HSD11B1 (0.43) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL7710713 | 0.80 | CHRNB2 (0.39) | HSD11B1TSHRCYP2C9LMNAEPHX1 | |
| Adamantane SCHEMBL27239 | 0.80 | FFAR3 (0.54) | HSD11B1TSHRCYP2C9CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599928-A1 | STABILIZED COMPLEX LIGANDS AND THEIR USE IN LIQUID CRYSTAL DISPLAYS. | HOECHST AG (DE) | 1994-06-08 | — | — | EP | disclosed |