Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adamantane SCHEMBL9316202 | 0.87 | HSD11B1 (0.46) | CYP2C9HSD11B1TSHREPHX2EPHX1 | |
| SCHEMBL3151607 | 0.84 | CHRNB2 (0.35) | CYP2C9HSD11B1TSHREPHX2EPHX1 | |
| Adamantane SCHEMBL7710713 | 0.84 | CHRNB2 (0.39) | CYP2C9HSD11B1TSHREPHX2EPHX1 | |
| Adamantane SCHEMBL3981833 | 0.82 | HSD11B1 (0.48) | CYP2C9HSD11B1TSHREPHX2EPHX1 | |
| Adamantane SCHEMBL974954 | 0.82 | HSD11B1 (0.48) | CYP2C9HSD11B1TSHREPHX2EPHX1 | |
| Adamantane SCHEMBL935449 | 0.82 | HSD11B1 (0.48) | CYP2C9HSD11B1TSHREPHX2EPHX1 | |
| Adamantane SCHEMBL3723679 | 0.78 | ALDH1A1 (0.50) | CYP2C9HSD11B1TSHREPHX2EPHX1 | |
| Adamantane SCHEMBL28221509 | 0.78 | HSD11B1 (0.46) | CYP2C9HSD11B1TSHREPHX2EPHX1 | |
| Adamantane SCHEMBL28005909 | 0.78 | LMNA (0.50) | CYP2C9HSD11B1TSHREPHX2EPHX1 | |
| Adamantane SCHEMBL34463641 | 0.75 | CHRNB2 (0.43) | EPHX2EPHX1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2023-06-22 | — | — | US | claimed |
| CN-111840527-B | Preparation method and application of shear-responsive nano drug delivery system | 郑州大学 | 2022-08-19 | — | — | CN | claimed |
| CN-113234183-B | Clathrate monomer based on subject-object recognition, preparation method thereof, starch-styrene-acrylic antibacterial emulsion, and preparation method and application thereof | 西北民族大学 | 2022-07-22 | — | — | CN | claimed |
| CN-113234183-A | Clathrate monomer based on subject-object recognition, preparation method thereof, starch-styrene-acrylic antibacterial emulsion, and preparation method and application thereof | 西北民族大学 | 2021-08-10 | — | — | CN | claimed |
| CN-112239410-A | Stable isotope deuterium-labeled rimantadine hydrochloride and synthesis method thereof | 上海安谱实验科技股份有限公司 | 2021-01-19 | — | — | CN | claimed |
| CN-110732027-A | stimulation response targeting polysaccharide supramolecular diagnosis and treatment assembly and preparation method thereof | 内蒙古农业大学 | 2020-01-31 | — | — | CN | claimed |
| US-12492220-B2 | Method for the preparation of oligonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2025-12-09 | — | — | US | disclosed |
| CN-118719157-A | Polymer-based photocatalytic material and preparation method and application thereof | 西北民族大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-117945913-A | Photosensitive resin composition containing polyimide precursor | 柔显(仙桃)光电半导体材料有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-115536557-B | Photoacid generator intermediate and preparation method of photoacid generator | 徐州博康信息化学品有限公司 | 2024-01-26 | — | — | CN | disclosed |
| EP-4298104-A1 | HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION | Agilent Technologies, Inc. (US) | 2024-01-03 | — | — | EP | disclosed |
| CN-116981676-A | Cyano-protected riboguanosine phosphoramidites for reducing depyrimidition caused by alkylamine exposure during final deprotection | 安捷伦科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2022183081-A9 | HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION | AGILENT TECHNOLOGIES, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5717083-A | COMPLEXING WITH PROTEINS, NUCLEIC ACIDS, LIPIDS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-10 | — | — | US | disclosed |
| US-5637684-A | BINDING PROTEINS, NUCLEIC ACIDS, LIPIDS; PHOSPHOLIPASE INHIBITOR | ISIS PHARMACEUTICALS, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0751948-A4 | NOVEL PHOSPHORAMIDATE AND PHOPHOROTHIOAMIDATE OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0751948-A1 | NOVEL PHOSPHORAMIDATE AND PHOPHOROTHIOAMIDATE OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1995023160-A1 | NOVEL PHOSPHORAMIDATE AND PHOPHOROTHIOAMIDATE OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1995-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12492220-B2 | Method for the preparation of oligonucleotides | POLN, POLRMT, POLI | CYP2C9 4624/4885HSD11B1 4325/4885TSHR 3504/4885 |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | POLN, POLRMT, POLI | CYP2C9 4624/4885HSD11B1 4325/4885TSHR 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.