Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adamantane SCHEMBL935449 | 0.84 | HSD11B1 (0.48) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL974954 | 0.84 | HSD11B1 (0.48) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL3981833 | 0.84 | HSD11B1 (0.48) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL28221509 | 0.80 | HSD11B1 (0.46) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL9316202 | 0.80 | HSD11B1 (0.46) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL27604496 | 0.78 | CYP2C9 (0.50) | HSD11B1TSHRCYP2C9LMNATHRB | |
| Adamantane SCHEMBL8402827 | 0.77 | FFAR3 (0.54) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL27239 | 0.77 | FFAR3 (0.54) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL28164719 | 0.77 | ACHE (0.54) | HSD11B1TSHRCYP2C9CYP2D6LMNA | |
| Adamantane SCHEMBL851674 | 0.75 | CYP2C9 (0.41) | HSD11B1TSHRCYP2C9EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501794-B2 | Compounds as cannabinoid receptor ligands | ABBVIE INC. (US) | 2013-08-06 | — | — | US | disclosed |
| CN-102272111-A | 1,2 -thiazol yl derivatives as cannabinoid receptor ligands | — | 2011-12-07 | — | — | CN | disclosed |
| US-20100234345-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234345-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | HSD11B1 2440/4885TSHR 285/4885CYP2C9 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.