Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321927 | 0.80 | ALOX5 (0.62) | ALOX5ALDH1A1MAPTCES2CES1 | |
| SCHEMBL9316635 | 0.79 | ALDH1A1 (0.67) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5409494 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTCES2CES1MEN1 | |
| SCHEMBL28100898 | 0.78 | POLB (0.60) | ALOX5ALDH1A1MAPTCES2CES1 | |
| SCHEMBL9316414 | 0.76 | MAPT (0.52) | ALDH1A1MAPTCES1MEN1KMT2A | |
| SCHEMBL8064713 | 0.75 | NPC1 (0.62) | ALOX5ALDH1A1MAPTCES2CES1 | |
| SCHEMBL357343 | 0.74 | HSPB1 (0.52) | ALDH1A1MAPTCES2CES1MEN1 | |
| SCHEMBL10745979 | 0.74 | CA1 (0.50) | ALDH1A1MAPTCES2CES1KMT2A | |
| SCHEMBL16398970 | 0.73 | ALOX5 (0.92) | ALOX5ALDH1A1MAPTCES2CES1 | |
| SCHEMBL8759518 | 0.72 | ALOX5 (0.59) | ALOX5ALDH1A1MAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281523-A | Adduct of serine hydrolase and nitrophenyl pnenacyl phosphonate | THE CATHOLIC UNIVERSITY OF AMERICA (US) | 1994-01-25 | — | — | US | claimed |