Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447871 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL9316639 | 0.79 | ALOX5 (0.54) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL1259531 | 0.78 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL9316414 | 0.76 | MAPT (0.52) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL9316440 | 0.72 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL1259532 | 0.72 | RAB9A (0.59) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL1259536 | 0.72 | RAB9A (0.59) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL2013298 | 0.71 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL6072613 | 0.70 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL527543 | 0.69 | MAPT (0.71) | ALDH1A1KMT2AMEN1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281523-A | Adduct of serine hydrolase and nitrophenyl pnenacyl phosphonate | THE CATHOLIC UNIVERSITY OF AMERICA (US) | 1994-01-25 | — | — | US | claimed |