SCHEMBL9316670

SCHEMBL9316670

CCNc1ccc(C(=O)NC(C)S(=O)(=O)CCO)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.37
CA1 P00915 6/20 0.37
ALDH1A1 P00352 5/20 0.37
LMNA P02545 2/20 0.37
RAB9A P51151 2/20 0.37
CYP1A2 P05177 1/20 0.37
ALOX15 P16050 1/20 0.37
CYP2C19 P33261 1/20 0.37
PTGS2 P35354 1/20 0.37
HPGD P15428 1/20 0.37
CA12 O43570 3/20 0.36
CA9 Q16790 3/20 0.36
HTT P42858 1/20 0.36
CTSS P25774 2/20 0.36
CTSL P07711 1/20 0.36
CTSK P43235 1/20 0.36
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317046 0.86 ALDH1A1 (0.41) CA2CA1ALDH1A1LMNACYP1A2
SCHEMBL9316984 0.82 NPC1 (0.49) CA2CA1ALDH1A1LMNARAB9A
SCHEMBL10294732 0.78 MLYCD (0.53) ALDH1A1LMNARAB9ACYP1A2ALOX15
SCHEMBL8517331 0.74 HDAC3 (0.44) CA2CA1ALDH1A1RAB9ACA12
SCHEMBL9316666 0.73 HDAC3 (0.43) CA2ALDH1A1RAB9AHPGDHTT
SCHEMBL9317025 0.73 TP53 (0.39) CA2ALDH1A1LMNAHPGD
SCHEMBL9316909 0.72 ALDH1A1 (0.46) CA2ALDH1A1LMNAHPGDNPC1
SCHEMBL10294776 0.69 PLK1 (0.61) CA2CA1LMNARAB9AHPGD
SCHEMBL2408925 0.69 HDAC1 (0.56) CA2CA1
SCHEMBL958453 0.69 MPO (0.55) CA2CA1ALDH1A1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5356440-A Fiber-reactive dyes containing only one sulfo group CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed