Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525076 | 0.65 | MEN1 (0.42) | PTPN1 | |
| SCHEMBL851567 | 0.65 | CHKA (0.50) | PTPN1 | |
| SCHEMBL8524528 | 0.64 | ALDH1A1 (0.42) | PTPN1 | |
| SCHEMBL249284 | 0.64 | CRHR1 (0.39) | PTPN1 | |
| SCHEMBL11246200 | 0.64 | SMN1; SMN2 (0.46) | PTPN1 | |
| SCHEMBL931882 | 0.64 | TRPV4 (0.34) | — | |
| SCHEMBL8055482 | 0.62 | ALDH1A1 (0.40) | PTPN1 | |
| SCHEMBL10694157 | 0.62 | CHKA (0.41) | PTPN1 | |
| SCHEMBL9278793 | 0.61 | PTPN1 (0.36) | PTPN1 | |
| SCHEMBL1018958 | 0.60 | ESR1 (0.45) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002408-A1 | NOVEL COMPOUNDS FOR TREATMENT OF NEURODEGENERATION ASSOCIATED WITH DISEASES, SUCH AS ALZHEIMER'S DISEASE OR DEMENTIA | ASTRAZENECA AB (SE) | 2011-01-06 | — | — | WO | disclosed |
| WO-2011002408-A1 | NOVEL COMPOUNDS FOR TREATMENT OF NEURODEGENERATION ASSOCIATED WITH DISEASES, SUCH AS ALZHEIMER'S DISEASE OR DEMENTIA | ASTRAZENECA AB (SE) | 2011-01-06 | — | — | WO | disclosed |